منابع مشابه
Interference by interferons: Janus faces in vascular proliferative diseases.
Interferons (IFNs) display pleiotropic properties; not only do they protect cells from viral infections but they may also modulate cell growth and differentiation as well as innate and adaptive immune responses. Therapeutic applications of IFNs have proven efficacy in a variety of illnesses, including hepatitis, multiple sclerosis, and some forms of cancer. Emerging evidence has been obtained d...
متن کاملInterferons
nterferons, naturally occuring glycoproteins with molecular weights of approximately 20,000 daltons, possess antiviral, antiproliferative, and immune-stimulating properties. They are classified into 3 antigenically distinct forms that are derived from different cell types. Alpha (or) interferons are derived from leukocytes, beta ([3) interferons from fibroblasts, and gamma (/) interferons from ...
متن کاملConvenient assay for interferons.
A convenient assay for interferons based on reduction of cytopathic effect was developed. The number of manipulations and the lengths of the various incubation steps were reduced to a minimum. The assay is simple to perform and can be completed within 16 h. Moreover, it can be used with various types of cells and a variety of viruses.
متن کاملRabbit Macrophage Interferons
Interferon is produced in cultures of rabbit leukocytes in response to infection with Newcastle disease virus or in the absence of known viral infection. The macrophage appears to be the responsible producing cell. Cultures prepared from sterile peritoneal exudates, which contained about 90% macrophages, are at least as efficient as cultures of rabbit kidney (RK) cells in their capacity to synt...
متن کاملInterferons and microRNAs.
Plants rely heavily on an adaptive RNA degradation system mediated by an RNA interference mechanism to combat viral infection, whereas mammals fight infection with specific antibodies and lymphocytes that are adapted to specific viral antigens, and also employ nonadaptive defenses, such as production of interferons (IFNs) that block viral replication and stimulate the host immune response. Ther...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2008
ISSN: 1945-3477
DOI: 10.1038/scibx.2008.398